CD8a Monoclonal / eFluor 506 / RPA-T8

Citations: (18)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 69-0088-42 (View supplier product page)
Size 100 Tests
Price $311.00
Antigen CD8a
Clone RPA-T8
Host Mouse
Isotype IgG1 κ
Conjugate eFluor 506
Target Species Human
Applications FC
Description CD8a Monoclonal Antibody (RPA-T8), eFluor 506, eBioscience
About CD8a and eFluor 506
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
eFluor 506 eFluor™ 506 (eF506) from Thermo Fisher Scientific has an excitation peak at 405 nm and an emission peak at 506 nm. It is useful in flow cytometry applications.
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eFluor 506 Excitation and Emission Spectra