CD8a Monoclonal / PE-Cy5 / 53-6.7

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 15-0081-83 (View supplier product page)
Size 200 μg
Price $413.00
Antigen CD8a
Clone 53-6.7
Host Rat
Isotype IgG2a κ
Conjugate PE-Cy5
Target Species Mouse
Applications FC
Description CD8a Monoclonal Antibody (53-6.7), PE-Cyanine5, eBioscience
About CD8a and PE-Cy5
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
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PE-Cy5 Excitation and Emission Spectra