CD86 Monoclonal / Alexa Fluor 488 / IT2.2

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 53-0869-41 (View supplier product page)
Size 25 Tests
Price $156.00
Antigen CD86
Clone IT2.2
Host Mouse
Isotype IgG2b κ
Conjugate Alexa Fluor 488
Target Species Human
Applications FC
Description CD86 (B7-2) Monoclonal Antibody (IT2.2), Alexa Fluor 488, eBioscience
About CD86 and Alexa Fluor 488
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra