CD45 Monoclonal / SuperBright 645 / 2D1

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 64-9459-42 (View supplier product page)
Size 100 Tests
Price $378.00
Antigen CD45
Clone 2D1
Host Mouse
Isotype IgG1 κ
Conjugate SuperBright 645
Target Species Human
Applications FC
Description CD45 Monoclonal Antibody (2D1), Super Bright 645, eBioscience
About CD45 and SuperBright 645
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
SuperBright 645 SuperBright 645 (SB645) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 645 nm. SB645 is spectrally similar to StarBright Violet 670 and BV650. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
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SuperBright 645 Excitation and Emission Spectra