CD38 Monoclonal / PerCP-eFluor 710 / HB7

Citations: (7)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 46-0388-42 (View supplier product page)
Size 100 Tests
Price $390.00
Antigen CD38
Clone HB7
Host Mouse
Isotype IgG1 κ
Conjugate PerCP-eFluor 710
Target Species Human
Applications FC
Description CD38 Monoclonal Antibody (HB7), PerCP-eFluor 710, eBioscience
About CD38 and PerCP-eFluor 710
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
PerCP-eFluor 710 PerCP-eFluor™ 710 (PerCP-eF710) is a red-emitting tandem fluorophore that combines PerCP and eF710. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, eF710, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-eF710 has an excitation peak at 482 nm and an emission peak at 710 nm, and is considered a slightly-red shifted but brighter alternative to PerCP-Cy5.5. This dye and associated products are mostly used for flow cytometry. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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PerCP-eFluor 710 Excitation and Emission Spectra