IL-21 R Monoclonal / PerCP-eFluor 710 / 2SX21R

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 46-3601-42 (View supplier product page)
Size 100 Tests
Price $418.00
Antigen IL-21 R
Clone 2SX21R
Host Mouse
Isotype IgG1 κ
Conjugate PerCP-eFluor 710
Target Species Human
Applications FC
Description CD360 (IL-21 Receptor) Monoclonal Antibody (2SX21R), PerCP-eFluor 710, eBioscience
About IL-21 R and PerCP-eFluor 710
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
PerCP-eFluor 710 PerCP-eFluor™ 710 (PerCP-eF710) is a red-emitting tandem fluorophore that combines PerCP and eF710. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, eF710, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-eF710 has an excitation peak at 482 nm and an emission peak at 710 nm, and is considered a slightly-red shifted but brighter alternative to PerCP-Cy5.5. This dye and associated products are mostly used for flow cytometry. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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PerCP-eFluor 710 Excitation and Emission Spectra