CD294 Monoclonal / PE / BM16

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 12-2949-41 (View supplier product page)
Size 25 Tests
Price $138.00
Antigen CD294
Clone BM16
Host Rat
Isotype IgG2a κ
Conjugate PE
Target Species Human
Applications FC
Description CD294 (CRTH2) Monoclonal Antibody (BM16), PE, eBioscience
About CD294 and PE
CD294 This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.[provided by RefSeq, Mar 2011]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra