PD-1 Monoclonal / PerCP-eFluor 710 / MIH4

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 46-9969-41 (View supplier product page)
Size 25 Tests
Price $179.00
Antigen PD-1
Clone MIH4
Host Mouse
Isotype IgG1 κ
Conjugate PerCP-eFluor 710
Target Species Human
Applications FC
Description CD279 (PD-1) Monoclonal Antibody (MIH4), PerCP-eFluor 710, eBioscience
About PD-1 and PerCP-eFluor 710
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
PerCP-eFluor 710 PerCP-eFluor™ 710 (PerCP-eF710) is a red-emitting tandem fluorophore that combines PerCP and eF710. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, eF710, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-eF710 has an excitation peak at 482 nm and an emission peak at 710 nm, and is considered a slightly-red shifted but brighter alternative to PerCP-Cy5.5. This dye and associated products are mostly used for flow cytometry. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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PerCP-eFluor 710 Excitation and Emission Spectra