PD-1 Monoclonal / PE / eBioJ105 (J105)

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 12-2799-41 (View supplier product page)
Size 25 Tests
Price $180.00
Antigen PD-1
Clone eBioJ105 (J105)
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human, Rhesus macaque
Applications FC
Description CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), PE, eBioscience
About PD-1 and PE
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra