PD-1 Monoclonal / eFluor 506 / J43

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Product Details
Supplier Thermo Fisher Scientific
Catalog #: 69-9985-82 (View supplier product page)
Size 100 μg
Price $317.00
Antigen PD-1
Clone J43
Host Armenian Hamster
Isotype IgG
Conjugate eFluor 506
Target Species Mouse
Applications FC
Description CD279 (PD-1) Monoclonal Antibody (J43), eFluor 506, eBioscience
About PD-1 and eFluor 506
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
eFluor 506 eFluor™ 506 (eF506) from Thermo Fisher Scientific has an excitation peak at 405 nm and an emission peak at 506 nm. It is useful in flow cytometry applications.
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eFluor 506 Excitation and Emission Spectra