PD-1 Monoclonal / APC / J43

Citations: (30)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 17-9985-82 (View supplier product page)
Size 100 μg
Price $352.00
Antigen PD-1
Clone J43
Host Armenian Hamster
Isotype IgG
Conjugate APC
Target Species Mouse
Applications FC
Description CD279 (PD-1) Monoclonal Antibody (J43), APC, eBioscience
About PD-1 and APC
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra