CCR6 Monoclonal / PE / R6H1

Citations: (10)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 12-1969-42 (View supplier product page)
Size 100 Tests
Price $373.00
Antigen CCR6
Clone R6H1
Host Mouse
Isotype IgG1 κ
Conjugate PE
Target Species Human
Applications FC
Description CD196 (CCR6) Monoclonal Antibody (R6H1), PE, eBioscience
About CCR6 and PE
CCR6 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
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PE Excitation and Emission Spectra