CD16 SuperBright 702 (3G8, Mouse) - Reactivity: Baboon, Chimpanzee, Cynomolgus macaque, Human, Non-Human Primate, Rhesus macaque
Product Details
| Description | CD16 Monoclonal Antibody (3G8), Super Bright 702, eBioscience | |
|---|---|---|
| Conjugate | SuperBright 702 | |
| Clone | 3G8 | |
| Target Species | Baboon, Chimpanzee, Cynomolgus macaque, Human, Non-Human Primate, Rhesus macaque | |
| Applications | FC | |
| Supplier | Thermo Fisher Scientific | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD16
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
About SuperBright 702
SuperBright 702 (SB702) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 702 nm. SB702 is spectrally similar to StarBright Violet 710 and BV711. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
SuperBright 702 (SB702) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 702 nm. SB702 is spectrally similar to StarBright Violet 710 and BV711. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience.
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