CD14 Monoclonal / PE-eFluor 610 / 61D3

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Product Details
Supplier Thermo Fisher Scientific
Catalog #: 61-0149-42 (View supplier product page)
Size 100 Tests
Price $352.00
Antigen CD14
Clone 61D3
Host Mouse
Isotype IgG1 κ
Conjugate PE-eFluor 610
Target Species Human
Applications FC
Description CD14 Monoclonal Antibody (61D3), PE-eFluor 610, eBioscience
About CD14 and PE-eFluor 610
CD14 The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
PE-eFluor 610 PE-eFluor™ 610 (PE-eF610, RPE-eF610) from Thermo Fisher Scientific is an orange-emitting tandem fluorophore that combines pycoerythrin (PE) and eFluor™ 610. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, eF610, which emitts light that can be captured with a 610/20 nm bandpass filter. PE-eF610 has an excitation peak at 565 nm and an emission peak at 607 nm, and is suitable alternative to PE-Texas Red®. PE-eF610 is mainly used for flow cytometry. This tandem is often a great option because of PE is excitable by multiple lasers due to its broad excitation spectrum and the eFluor™ 610 acceptor molecule emits brightly in the Orange/Red spectrum. Many cytometers are commonly set up with the 610/20 bandpass filter that can detect this fluorophore's emission. This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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PE-eFluor 610 Excitation and Emission Spectra