CD11b Monoclonal / APC-eFluor 780 / ICRF44

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 47-0118-41 (View supplier product page)
Size 25 Tests
Price $162.00
Antigen CD11b
Clone ICRF44
Host Mouse
Isotype IgG1 κ
Conjugate APC-eFluor 780
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description CD11b Monoclonal Antibody (ICRF44), APC-eFluor 780, eBioscience
About CD11b and APC-eFluor 780
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
APC-eFluor 780 APC-eFluor™ 780 (APC-eF780) is a red-emitting tandem fluorophore of APC, excited by the 640 nm red laser and transfers energy to the acceptor, eF780, which emits light that can be captured with a 780/60 nm bandpass filter. APC-eF780 has an excitation peak at 645 nm and an emission peak at 767 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is part of the larger eFluor™ dye family, developed by eBioscience which is now part of ThermoFisher Scientific.
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APC-eFluor 780 Excitation and Emission Spectra