CD11b Monoclonal / PE-Cy5 / M1/70

Citations: (191)
Product Details
Supplier Thermo Fisher Scientific
Catalog #: 15-0112-82 (View supplier product page)
Size 100 μg
Price $259.00
Antigen CD11b
Clone M1/70
Host Rat
Isotype IgG2b κ
Conjugate PE-Cy5
Target Species Mouse
Applications FC
Description CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience
About CD11b and PE-Cy5
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
PE-Cy5 PE-Cyanine®5 (PE-Cy5) is a red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy5. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy5. PE-Cy5 has an excitation peak at 496 nm and an emission peak at 667 nm.
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PE-Cy5 Excitation and Emission Spectra