FluoroFinder

	Supplier	Miltenyi Biotec
	Catalog #:	130-122-943 (View supplier product page)
	Size	30 µg in 200 µL
	Price	$95.00
	Antigen	CD3
	Clone	REA641
	Host	Human
	Isotype	IgG1
	Conjugate	APC
	Target Species	Mouse
	Applications	FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, 3D-IF
	Description	Clone REA641 recognizes the mouse CD3 complex, which is expressed on all mature T lymphocytes, NKT cells, and during the development of thymocytes. CD3, also known as T3, belongs to the Ig superfamily. It consists of CD3ε, δ, γ, and ζ chains and forms a TCR complex by associating with TCR α/β or γ/δ chains. The TCR does not possess intracellular signaling domains, uncoupling Ag recognition from T cell signaling. The TCR is instead non-covalently associated with a multisubunit signaling apparatus, consisting of the CD3εγ and CD3εδ heterodimers and the CD3ζζ homodimer, which collectively form the TCR-CD3 complex. CD3 is involved in T cell activation, signal transduction, and antigen recognition by binding the peptide/MHC antigen complex. \| Additional information: Clone REA641 displays negligible binding to Fc receptors.

$95.00
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CD3 / APC / REA641