SLC22A18 / Unconjugated / Polyclonal

Product Details
Supplier Atlas Antibodies
Catalog #: HPA071461 (View supplier product page)
Size 100 μl
Price $439.00
Antigen SLC22A18
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description solute carrier family 22, member 18
About SLC22A18 and Purified
SLC22A18 This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Several alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2015]
Citations
Additional
Sources
Reviews & Ratings
Purified Excitation and Emission Spectra