EphB2 / Unconjugated / Polyclonal

Product Details
Supplier Atlas Antibodies
Catalog #: HPA071200 (View supplier product page)
Size 100 μl
Price $439.00
Antigen EphB2
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, ICC/IF
Description EPH receptor B2
About EphB2 and Purified
EphB2 This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
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Purified Excitation and Emission Spectra