COCO / Unconjugated / Polyclonal

Product Details
Supplier Atlas Antibodies
Catalog #: HPA049472 (View supplier product page)
Size 100 μl
Price $439.00
Antigen COCO
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description DAN domain family member 5, BMP antagonist
About COCO and Purified
COCO This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra