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UBR1 Purified (Polyclonal, Rabbit) - Reactivity: Human
Product Details
| Description | ubiquitin protein ligase E3 component n-recognin 1 | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | IHC, ICC/IF | |
| Supplier | Atlas Antibodies | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About UBR1
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
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