HDAC5 / Unconjugated / Polyclonal

Citations: (1)
Product Details
Supplier Atlas Antibodies
Catalog #: HPA030991 (View supplier product page)
Size 100 μl
Price $439.00
Antigen HDAC5
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC, ICC/IF
Description histone deacetylase 5
About HDAC5 and Purified
HDAC5 Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra