ADAMTS5 / Unconjugated / Polyclonal

Product Details
Supplier Atlas Antibodies
Catalog #: HPA005661 (View supplier product page)
Size 100 μl
Price $439.00
Antigen ADAMTS5
Clone Polyclonal
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description ADAM metallopeptidase with thrombospondin type 1 motif, 5
About ADAMTS5 and Purified
ADAMTS5 This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]
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Purified Excitation and Emission Spectra