CD8a / Unconjugated / 2.43

Product Details
Supplier Bio X Cell
Catalog #: BP0061-50MG (View supplier product page)
Size 50 mg
Price $3,619.00
Antigen CD8a
Clone 2.43
Host Rat
Isotype IgG2b κ
Conjugate Unconjugated
Target Species Mouse
Applications Depletion
Description InVivoPlus anti-mouse CD8alpha, Clone: 2.43, Size: 50 mg
About CD8a and Purified
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
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Purified Excitation and Emission Spectra