CD5 / APC-Vio770 / UCHT2

Product Details
Supplier Miltenyi Biotec
Catalog #: 130-119-852 (View supplier product page)
Size 100 tests in 200 µL
Price $365.00
Antigen CD5
Clone UCHT2
Host Mouse
Isotype IgG1,κappa
Conjugate APC-Vio770
Target Species Human
Applications FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC, Mass Cytometry
Description Clone UCHT2 reacts with human CD5, a 67 kDa single-chain transmembrane glycoprotein. It is expressed on most thymocytes, the majority of peripheral T cells, a subpopulation of B cells, and B cell chronic lymphocytic leukemia (B-CLL) cells.
About CD5 and APC-Vio770
CD5 This gene encodes a member of the scavenger receptor cysteine-rich (SRCR) superfamily. Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system. This protein is a type-I transmembrane glycoprotein found on the surface of thymocytes, T lymphocytes and a subset of B lymphocytes. The encoded protein contains three SRCR domains and may act as a receptor to regulate T-cell proliferation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2016]
APC-Vio770 APC-Vio®770 from Miltenyi is a tandem fluorophore with APC as the donor and has an excitation peak at 652 nm and an emission peak at 775 nm, and is spectrally similar to APC-Cy® 7 (GE Healthcare) APC-H7 (BD Biosciences), APC-eFluor™ 780 (ThermoFisher Scientific), APC-Vio®770 (Miltenyi Biotec), and APC-Fire™ 750 (BioLegend). The Vio® dye family are products of Miltenyi Biotec, with many antibody conjugates designed and validated for flow cytometry.
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APC-Vio770 Excitation and Emission Spectra