CD137 / PE / 4B4-1
CD137 / PE / 4B4-1
Citations:
(13)
Product Details
| Supplier | Miltenyi Biotec | |
|---|---|---|
| Catalog #: | 130-119-885 (View supplier product page) | |
| Size | 100 tests in 200 µL | |
| Price | $320.00 | |
| Antigen | CD137 | |
| Clone | 4B4-1 | |
| Host | Mouse | |
| Isotype | IgG1,κappa | |
| Conjugate | PE | |
| Target Species | Human | |
| Applications | FC, MICS (MACSima Imaging Cyclic Staining), IF, IHC | |
| Description | This antibody recognizes the CD137 (4-1BB) antigen, a 30 kDa glycoprotein of the tumor necrosis factor (TNF) receptor superfamily. CD137 is mainly expressed on activated CD4+ and CD8+ T cells, activated B cells, and natural killer cells, but can also be found on resting monocytes and dendritic cells. | As a costimulatory molecule it is involved in the activation and survival of CD4+ or CD8+ T cells, and NK cells. CD137 has been described to be a suitable marker for antigen-specific activation of human CD8+ T cells, as it is not expressed on resting CD8+ T cells and its expression is reliably induced after 24 hours of stimulation. |
Citations
| PMID 17371945 | ||
|---|---|---|
| PMID 16931626 | ||
| Additional Sources |
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Reviews & Ratings
PE Excitation and Emission Spectra
$320.00
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