PD-1 / Brilliant Blue 700 / J43

Citations: (2)
Product Details
Supplier BD Biosciences
Catalog #: 566515 (View supplier product page)
Size 25 μg
Price $140.00
Antigen PD-1
Clone J43
Host Armenian Hamster
Isotype IgG2 κ
Conjugate Brilliant Blue 700
Target Species Mouse
Applications FC
Description Ms CD279 (PD-1) BB700 J43 25ug
About PD-1 and Brilliant Blue 700
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
Brilliant Blue 700 Horizon Brilliant™ Blue 700 (BB700) from BD Biosciences is a tandem dye of BB515. It has an excitation peak at 484 nm and an emission peak at 695 nm, making it spectrally comparable to PerCP-Cy5.5.
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Brilliant Blue 700 Excitation and Emission Spectra