Neurexin 1 Polyclonal / Unconjugated /
Neurexin 1 Polyclonal / Unconjugated /
Product Details
| Supplier | Thermo Fisher Scientific | |
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| Catalog #: | PA5-18730 (View supplier product page) | |
| Size | 100 μg | |
| Price | $436.00 | |
| Antigen | Neurexin 1 | |
| Clone | ||
| Host | Goat | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | FC, WB | |
| Description | NRXN1 Polyclonal Antibody |
About Neurexin 1 and Purified
| Neurexin 1 | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016] |
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Images
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Flow cytometric analysis of NRXN1 in HepG2 cells using an NRXN1 monoclonal antibody (Product # PA5-18730) at 10 µg/mL for 1hr, depicted by the blue line. The cells were paraformaldehyde fixed and permeabilized with 0.5% Triton. Primary incubation followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody. |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$436.00
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