ITCH Polyclonal / Unconjugated /
ITCH Polyclonal / Unconjugated /
Product Details
| Supplier | Thermo Fisher Scientific | |
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| Catalog #: | PA5-18662 (View supplier product page) | |
| Size | 100 μg | |
| Price | $446.00 | |
| Antigen | ITCH | |
| Clone | ||
| Host | Goat | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | FC, WB, IHC, IP | |
| Description | ITCH Polyclonal Antibody |
About ITCH and Purified
| ITCH | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
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Images
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Flow cytometric analysis of ITCH in HeLa cells using a ITCH monoclonal antibody (Product # PA5-18662) at 10 µg/mL for 1hr, depicted by the blue line. The cells were paraformaldehyde fixed and permeabilized with 0.5% Triton. Primary incubation followed by Alexa Fluor 488 secondary antibody (1 µg/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody. |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$446.00
Supplier Page
Supplier Page
