CD8a Monoclonal / SuperBright 436 / YCATE55.9
CD8a Monoclonal / SuperBright 436 / YCATE55.9
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 62-5080-42 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $377.00 | |
| Antigen | CD8a | |
| Clone | YCATE55.9 | |
| Host | Rat | |
| Isotype | IgG1 κ | |
| Conjugate | SuperBright 436 | |
| Target Species | Canine | |
| Applications | FC | |
| Description | CD8a Monoclonal Antibody (YCATE55.9), Super Bright 436, eBioscience |
About CD8a and SuperBright 436
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| SuperBright 436 | SuperBright 436 (SB436) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 436 nm. SB436 is spectrally similar to StarBright Violet 440, eFluor™ 450 and Pacific Blue but can be unmixed with Brilliant™ Violet 421 on a spectral analyzer. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Staining of normal canine peripheral blood cells with CD4 Monoclonal Antibody, PE-Cyanine7 (Product # 25-5040-42) and Rat IgG1 kappa Isotype Control, Super Bright 436 (Product # 62-4301-82) (left) or CD8a Monoclonal Antibody, Super Bright 436 (right). Viable cells, as determined by 7-AAD (Product # 00-6993-50) were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 436 Excitation and Emission Spectra
$377.00
Supplier Page
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