CCR7 Monoclonal / SuperBright 600 / 3D12
CCR7 Monoclonal / SuperBright 600 / 3D12
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 63-1979-42 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $394.00 | |
| Antigen | CCR7 | |
| Clone | 3D12 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | SuperBright 600 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD197 (CCR7) Monoclonal Antibody (3D12), Super Bright 600, eBioscience |
About CCR7 and SuperBright 600
| CCR7 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] | |
|---|---|---|
| SuperBright 600 | SuperBright 600 (SB600) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 600 nm. SB600 is spectrally similar to StarBright Violet 610 and BV605. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells were stained with CD45RA Monoclonal Antibody, FITC (Product # 11-0458-42) and Rat IgG2a kappa Isotype Control, Super Bright 600 (Product # 63-4321-82) (left) or CD197 (CCR7) Monoclonal Antibody, Super Bright 600 (right). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 600 Excitation and Emission Spectra
$394.00
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