CD45 Monoclonal / SuperBright 780 / 2D1
CD45 Monoclonal / SuperBright 780 / 2D1
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 78-9459-42 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $369.00 | |
| Antigen | CD45 | |
| Clone | 2D1 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | SuperBright 780 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD45 Monoclonal Antibody (2D1), Super Bright 780, eBioscience |
About CD45 and SuperBright 780
| CD45 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] | |
|---|---|---|
| SuperBright 780 | SuperBright 780 (SB780) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 780 nm. SB780 is spectrally similar to StarBright Violet 790 and BV785. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells were stained with Mouse IgG1 kappa Isotype Control, Super Bright 780 (Product # 78-4714-82) (blue histogram) or CD45 Monoclonal Antibody, Super Bright 780 (purple histogram). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 780 Excitation and Emission Spectra
$369.00
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