CCR7 Monoclonal / SuperBright 780 / 3D12
CCR7 Monoclonal / SuperBright 780 / 3D12
Citations:
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Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 78-1979-41 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $216.00 | |
| Antigen | CCR7 | |
| Clone | 3D12 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | SuperBright 780 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD197 (CCR7) Monoclonal Antibody (3D12), Super Bright 780, eBioscience |
About CCR7 and SuperBright 780
| CCR7 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] | |
|---|---|---|
| SuperBright 780 | SuperBright 780 (SB780) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 780 nm. SB780 is spectrally similar to StarBright Violet 790 and BV785. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells cells were stained with CD45RA Monoclonal Antibody, FITC (Product # 11-0458-42) and Rat IgG2a kappa Isotype Control, Super Bright 780 (Product # 78-4321-82) (left) or CD197 (CCR7) Monoclonal Antibody, Super Bright 780 (right). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 780 Excitation and Emission Spectra
$216.00
Supplier Page
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