FluoroFinder

	Supplier	Thermo Fisher Scientific
	Catalog #:	12-9338-42 (View supplier product page)
	Size	100 Tests
	Price	$434.00
	Antigen	IL-33 R
	Clone	hIL33Rcap
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	PE
	Target Species	Human
	Applications	FC
	Description	IL-33R (ST2) Monoclonal Antibody (hIL33Rcap), PE, eBioscience

	IL-33 R	The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

		LAD2 cells were stained with Mouse IgG1 kappa Isotype Control, PE (Product # 12-4714-82) (blue histogram) or IL-33R (ST2) Monoclonal Antibody, PE (purple histogram). Total viable cells were used for analysis, as determined by Fixable Viability Dye eFluor 450 (Product # 65-0863-18).
		HEK293T cells were transduced to express IL-33R-GFP fusion protein. The cells were then stained with Mouse IgG1 kappa Isotype Control, PE (Product # 12-4714-82) (left panel) or IL-33R (ST2) Monoclonal Antibody, PE (right panel). Total viable cells were used for analysis.