CD59 Monoclonal / SuperBright 645 / OV9A2
CD59 Monoclonal / SuperBright 645 / OV9A2
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 64-0596-42 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $419.00 | |
| Antigen | CD59 | |
| Clone | OV9A2 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | SuperBright 645 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD59 (Protectin) Monoclonal Antibody (OV9A2), Super Bright 645, eBioscience |
About CD59 and SuperBright 645
| CD59 | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| SuperBright 645 | SuperBright 645 (SB645) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 645 nm. SB645 is spectrally similar to StarBright Violet 670 and BV650. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells were stained with Mouse IgG1 kappa Isotype Control, Super Bright 645 (Product # 64-4714-82) (blue histogram) or CD59 Monoclonal Antibody, Super Bright 645 (purple histogram). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 645 Excitation and Emission Spectra
$419.00
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