PD-1 Monoclonal / SuperBright 645 / eBioJ105 (J105)
PD-1 Monoclonal / SuperBright 645 / eBioJ105 (J105)
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 64-2799-42 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $373.00 | |
| Antigen | PD-1 | |
| Clone | eBioJ105 (J105) | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | SuperBright 645 | |
| Target Species | Human, Rhesus macaque | |
| Applications | FC | |
| Description | CD279 (PD-1) Monoclonal Antibody (eBioJ105 (J105)), Super Bright 645, eBioscience |
About PD-1 and SuperBright 645
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| SuperBright 645 | SuperBright 645 (SB645) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 645 nm. SB645 is spectrally similar to StarBright Violet 670 and BV650. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells were unstimulated (orange histogram) or stimulated with PHA-L (Product # 00-4977). Cells were then stained with Mouse IgG1 kappa Isotype Control, Super Bright 645 (Product # 64-4714-82) (blue histogram) or CD279 Monoclonal Antibody, Super Bright 645 (purple histogram). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 645 Excitation and Emission Spectra
$373.00
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