CD268 Monoclonal / SuperBright 645 / 8A7
CD268 Monoclonal / SuperBright 645 / 8A7
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 64-9117-41 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $194.00 | |
| Antigen | CD268 | |
| Clone | 8A7 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | SuperBright 645 | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD268 (BAFF Receptor) Monoclonal Antibody (8A7), Super Bright 645, eBioscience |
About CD268 and SuperBright 645
| CD268 | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| SuperBright 645 | SuperBright 645 (SB645) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 645 nm. SB645 is spectrally similar to StarBright Violet 670 and BV650. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Normal human peripheral blood cells were stained with CD19 Monoclonal Antibody, APC (Product # 17-0199-42) and Mouse IgG2a kappa Isotype Control, Super Bright 645 (Product # 64-4724-82) (left) or CD268 (BAFF Receptor) Monoclonal Antibody, Super Bright 645 (right). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 645 Excitation and Emission Spectra
$194.00
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