CD85j / Alexa Fluor 700 / HP-F1

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 56-5129-41 (View supplier product page)
Size 25 Tests
Price $145.00
Antigen CD85j
Clone HP-F1
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 700
Target Species Human
Applications FC
Description CD85j (ILT2) Monoclonal Antibody (HP-F1), Alexa Fluor 700, eBioscience
About CD85j and Alexa Fluor 700
CD85j This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
Images
  CD85j Alexa Fluor 700 Thermo Fisher Scientific antibody anti target:Human host:Mouse isotype:IgG1 κ clone:HP-F1 Normal human peripheral blood cells were stained with CD11b Monoclonal Antibody, PE (Product # 12...

Normal human peripheral blood cells were stained with CD11b Monoclonal Antibody, PE (Product # 12-0118-42) and Mouse IgG1 kappa Isotype Control, Alexa Fluor 700 (Product # 56-4714-80) (left) or CD85j (ILT2) Monoclonal Antibody, Alexa Fluor 700 (right). Cells in the monocyte gate were used for analysis.

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Alexa Fluor 700 Excitation and Emission Spectra