COCO Monoclonal / Unconjugated / OTI2H3

Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA5-25684 (View supplier product page)
Size 100 μl
Price $486.00
Antigen COCO
Clone OTI2H3
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications FC, IHC-P, WB
Description DAND5 Monoclonal Antibody (OTI2H3)
About COCO and Purified
COCO This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra