V-type proton ATPase subunit F Monoclonal / Unconjugated / OTI5F10

Product Details
Supplier Thermo Fisher Scientific
Catalog #: MA5-25408 (View supplier product page)
Size 100 μl
Price $486.00
Antigen V-type proton ATPase subunit F
Clone OTI5F10
Host Mouse
Isotype IgG2a
Conjugate Unconjugated
Target Species Canine, Human, Non-Human Primate, Rat
Applications IHC, FC, IHC-P, WB
Description ATP6V1F Monoclonal Antibody (OTI5F10)
About V-type proton ATPase subunit F and Purified
V-type proton ATPase subunit F This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008]
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Purified Excitation and Emission Spectra