PD-1 Monoclonal / SuperBright 645 / J43
PD-1 Monoclonal / SuperBright 645 / J43
Citations:
(1)
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 64-9985-82 (View supplier product page) | |
| Size | 100 μg | |
| Price | $377.00 | |
| Antigen | PD-1 | |
| Clone | J43 | |
| Host | Armenian Hamster | |
| Isotype | IgG | |
| Conjugate | SuperBright 645 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | CD279 (PD-1) Monoclonal Antibody (J43), Super Bright 645, eBioscience |
About PD-1 and SuperBright 645
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| SuperBright 645 | SuperBright 645 (SB645) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 645 nm. SB645 is spectrally similar to StarBright Violet 670 and BV650. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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C57BL/6 mouse splenocytes were stained with CD4 Monoclonal Antibody, eFluor 450 (Product # 48-0041-82) and 0.5 µg of Armenian Hamster IgG Isotype Control, Super Bright 645 (Product # 64-4888-82) (left) or 0.5 µg of CD279 Monoclonal Antibody, Super Bright 645 (right). Cells in the lymphocyte gate were used for analysis. |
Citations
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Reviews & Ratings
SuperBright 645 Excitation and Emission Spectra
$377.00
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