CD40 / SuperBright 780 / 1C10
CD40 / SuperBright 780 / 1C10
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 78-0401-80 (View supplier product page) | |
| Size | 25 μg | |
| Price | $145.00 | |
| Antigen | CD40 | |
| Clone | 1C10 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | SuperBright 780 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | CD40 Monoclonal Antibody (1C10), Super Bright 780, eBioscience |
About CD40 and SuperBright 780
| CD40 | This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014] | |
|---|---|---|
| SuperBright 780 | SuperBright 780 (SB780) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 780 nm. SB780 is spectrally similar to StarBright Violet 790 and BV785. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
|
SJL mouse splenocytes were stained with CD19 Monoclonal Antibody, eFluor 450 (Product # 48-0193-82) and 0.5 µg of Rat IgG2a kappa Isotype Control, Super Bright 780 (Product # 78-4321-82) (left) or 0.5 µg of CD40 Monoclonal Antibody, Super Bright 780 (right). Cells in the lymphocyte gate were used for analysis. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
SuperBright 780 Excitation and Emission Spectra
$145.00
Supplier Page
Supplier Page
