PD-1 Monoclonal / SuperBright 436 / RMP1-30
PD-1 Monoclonal / SuperBright 436 / RMP1-30
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 62-9981-82 (View supplier product page) | |
| Size | 100 μg | |
| Price | $363.00 | |
| Antigen | PD-1 | |
| Clone | RMP1-30 | |
| Host | Rat | |
| Isotype | IgG2b κ | |
| Conjugate | SuperBright 436 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | CD279 (PD-1) Monoclonal Antibody (RMP1-30), Super Bright 436, eBioscience |
About PD-1 and SuperBright 436
| PD-1 | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| SuperBright 436 | SuperBright 436 (SB436) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 436 nm. SB436 is spectrally similar to StarBright Violet 440, eFluor™ 450 and Pacific Blue but can be unmixed with Brilliant™ Violet 421 on a spectral analyzer. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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BALB/c mouse splenocytes were unstimulated (left) or stimulated with CD3e and CD28 Monoclonal Antibodies, Functional Grade (Product # 16-0031-85 and Product # 16-0281-85) (right). Cells were then stained with 0.5 µg of Rat IgG2b kappa Isotype Control, Super Bright 436 (Product # 62-4031-82) (blue histogram) or CD279 Monoclonal Antibody, Super Bright 436 (purple histogram).Total viable cells were used for analysis, as determined by 7-AAD (Product # 00-6993-50). |
Citations
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Reviews & Ratings
SuperBright 436 Excitation and Emission Spectra
$363.00
Supplier Page
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