CD45 Monoclonal / SuperBright 436 / 30-F11
CD45 Monoclonal / SuperBright 436 / 30-F11
Citations:
(2)
Product Details
| Supplier | Thermo Fisher Scientific | |
|---|---|---|
| Catalog #: | 62-0451-82 (View supplier product page) | |
| Size | 100 μg | |
| Price | $363.00 | |
| Antigen | CD45 | |
| Clone | 30-F11 | |
| Host | Rat | |
| Isotype | IgG2b κ | |
| Conjugate | SuperBright 436 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | CD45 Monoclonal Antibody (30-F11), Super Bright 436, eBioscience |
About CD45 and SuperBright 436
| CD45 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] | |
|---|---|---|
| SuperBright 436 | SuperBright 436 (SB436) is a fluorescent polymer with an excitation peak at 414 nm and an emission peak at 436 nm. SB436 is spectrally similar to StarBright Violet 440, eFluor™ 450 and Pacific Blue but can be unmixed with Brilliant™ Violet 421 on a spectral analyzer. This dye is a member of the SuperBright dye family, sold by ThermoFisher Scientific under license from BD Bioscience. |
Images
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Swiss Webster mouse bone marrow cells were stained with TER-119 Monoclonal Antibody, PE (Product # 12-5921-82) and 0.25 µg of Rat IgG2b kappa Isotype Control, Super Bright 436 (Product # 62-4031-82) (left) or 0.25 µg of CD45 Monoclonal Antibody, Super Bright 436 (right). Total viable cells were used for analysis, as determined by 7-AAD (Product # 00-6993-50). |
Citations
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Reviews & Ratings
SuperBright 436 Excitation and Emission Spectra
$363.00
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