Serotonin N-acetyltransferase / DyLight 488 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-135G (View supplier product page)
Size 0.1 ml
Price $464.00
Antigen Serotonin N-acetyltransferase
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Bovine (Negative), Chicken (Negative), Human, Primate, Rat (Negative), Zebrafish (Negative)
Applications WB, ICC/IF
Description This is specific for primate AANAT (3,4).
About Serotonin N-acetyltransferase and DyLight 488
Serotonin N-acetyltransferase The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra