BLNK / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ91859-50μl (View supplier product page)
Size 50 μl
Price $153.45
Antigen BLNK
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, IHC, ELISA
About BLNK and Purified
BLNK This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
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Purified Excitation and Emission Spectra