PSAP / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ160017-1ml (View supplier product page)
Size 1 ml
Price $899.00
Antigen PSAP
Clone
Host Mouse
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications IHC
Description Mouse monoclonal to PSAP
About PSAP and Purified
PSAP This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Citations
Additional
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Reviews & Ratings
Purified Excitation and Emission Spectra