CSK / Biotin /

Product Details
Supplier St John's Laboratory
Catalog #: STJ73187-100μg (View supplier product page)
Size 100 μg
Price $403.00
Antigen CSK
Clone
Host Goat
Isotype IgG
Conjugate Biotin
Target Species Bovine, Canine, Human, Mouse, Rat
Applications ELISA, WB, IHC
Description Goat polyclonal to CSK, Biotinylated
About CSK and Biotin
CSK The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
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Biotin Excitation and Emission Spectra