PRDM9 / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ71880-100μg (View supplier product page)
Size 100 μg
Price $325.50
Antigen PRDM9
Clone
Host Goat
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications ELISA
Description Goat polyclonal to PRDM9
About PRDM9 and Purified
PRDM9 The protein encoded by this gene is a zinc finger protein with histone methyltransferase activity that catalyzes histone H3 lysine 4 trimethylation (H3K4me3) during meiotic prophase. This protein contains multiple domains, including a Kruppel-associated box (KRAB) domain, an SSX repression domain (SSXRD), a PRD1-BF1 and RIZ homologous region, a subclass of SET (PR/SET) domain, and a tandem array of C2H2 zinc fingers. The zinc finger array recognizes a short sequence motif, leading to local H3K4me3, and meiotic recombination hotspot activity. The observed allelic variation alters the DNA-binding sequence specificity of the protein, resulting in distinct meiotic recombination hotspots amongst individuals and populations. Multiple alternate alleles of this gene have been described. [provided by RefSeq, Jul 2015]
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Purified Excitation and Emission Spectra