ITCH / Unconjugated /

Product Details
Supplier St John's Laboratory
Catalog #: STJ71108-100μg (View supplier product page)
Size 100 μg
Price $403.00
Antigen ITCH
Clone
Host Goat
Isotype IgG
Conjugate Unconjugated
Target Species Bovine, Canine, Human, Mouse, Rat
Applications ELISA, WB, IF, FC
Description Goat polyclonal to ITCH
About ITCH and Purified
ITCH This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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Purified Excitation and Emission Spectra